Does EZ Flash Omega require fixed ROMs, or can I remove them from my library to save storage space?

Currently my GBA ROM library for my EZ Flash Omega is around 34gb due to downloading an archive of every ROM with many file versions, and many of these are made up of standard versions: [f_4] versions and [f_5] versions. Will the EZ Flash Omega have any problems with the standard ROMs, or will I require the fixed ROMs? Or does compatibility vary from game-to-game? Thanks.